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AGTR1 1166A>C WT Reference Standard

CBPA0137

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產(chǎn)品描述
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Introduction  
Format Genomic DNA
Description G-protein-coupled receptors (GPCRs) are the largest family of transmembrane proteins in humans, and these receptors serve as important regulators of almost every aspect of human physiology. The angiotensin II type 1 receptor (AT1R) is a prototypical GPCR best known for its central role in maintaining cardiovascular and renal homeostasis. Binding of the AT1R’s endogenous agonist, the eight-residue peptide angiotensin II (AngII), triggers AT1R activation of the heterotrimeric G protein Gq, which in turn activates calcium signaling that culminates in vasoconstriction.
   
Technical Data 
Gene AGTR1
AA Change N/A
DNA Change NM_000685.5:c.*86A>C
Chr position (GRCh37) chr3:148459988 A>C
Allelic Frequency 0%
Zygosity Wild type
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

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